Ami shigella.Amake apnara shobai na chinleo medical college er 2nd
prof examinee ra shobai valo korei amake chene.Ar na chine jabe
koi?Exam pass korar jonno ami ottabosshokio.Amake niye bohu bochhor
dhore bohu scientist,doctor,student bohu research korechhen.Ami
prithibir manusher jonno 1 moha atongko.Protidin lakh lakh lok amar nam
nay oshroddha vore.Koti koti manushke ami sheba(?) diye dhonno
korechhi.Emonki kono raja badsha bikkhato kobi shahittik neta kauke
chhari nai.O,amar pesha ki tato bola hoy nai.Ami ja kori shetake manush
nam diyechhe 'Diarrhoea/Dysentry'.Bacteria jagote eta ottonto
shommanjonok pesha.Er maddhome bechara manush ra ato oshohay ar durbol
hoye jay,waw mojai alada.Amar nam lekha hoyechhe onek mota mota boi a.Ei
jemon dhorun 'Lange Microbiology, page142'.Obossho beshirvag student ja
pore ta holo Shakhawat page 3.121,Endevour page 226 etc.Ekhon ami amar
jibon brittanto likhte chai.Ami bacteria.
Amar kichhu 'PROPERTIES'-
1.Gram negative rods
2.Non lactose fermenter
3.We form colorless colonies on Mac Conkey's agar media.
4.Non motile
5.Fimbriae present
6.Aerobes or facultative anaerobes
7.Non spore forming and non capsulated
8.True intestinal.
Ami ja kori takey bola hoy Bacillary dysentry.Eita holo 'frequent painful passage of stools containing blood and mucous.'Vuktovogi matroi er moja ter peyecen.Apni na peye thakle amake janaben.Babostha korbo.
Amar main ostro jake apnara
'VIRULENCE FACTOR' bolen,shegulo holo-
1.Invasiveness
2.Exotoxin-shigella toxin,A & B chain
3.Endotoxin
Amra 4 vai.Apnader vashay 'SPECIES'.Eder namgulo holo-
1.Shigella dysenteriae
2.Shigella flexneri
3.Shigella boydii
4.Shigella sonnei.
Ebar ami apnader bolbo ami kivabe dysentry kori.Apnader vashay
PATHOGENESIS.
Route of entry-Faeco-oral
Infective dose-10-100 organisms to produce disease.
Process-
Terminal ileum>bacteria attach to surface epithelium>enters inside the cells>Spread into adjacent cells>upto lamina propria>replicate and colonize>acute inflammation>micro abscess formation>necrosis of surface epithelium>sloughing out of epithelium>ulcer formation and bleeding from mucosa>endotoxin irritates the bowel causing diarrhoea>organisms remaining localized & usually do not cause bacteremia.
Bachar jonno manushke khete hoy.Oneke acen tara shudhu khaoar jonnoi bachen.Je poriman khan,amaroi voy lage.Abar khushio hoi.Karon etai amar jatayater upojukto poth.Shujog bujhe ami dhuke jai thik peter vetor.Erpor kaj shuru.Oneke bolen 'moddhoprachche juddho shuru hoichhe'.Erpor tibro bege toilet er dike chhute giye comod a missile nikkhep.Ar amar nirapode prosthan.
Majhe majhe bipodeo porte hoy.Amar dhokar khobor peye jan keu keu.Eijonno ja kora hoy takey manushera bole
'DIAGNOSIS'.
Sheta kore evabe-
1.Specimen Collection:-
-Freshly passed stool
-Rectal swab
-Mucous
2.Stool examination:
*Naked eye examination-
Fresh stool
Mucous
Alkaline smell
Pus
*Chemical:
Alkaline in nature
*Microscopic:
Pus cells 90% polymorphs
Epithelial cells more
RBC numerous
Macrophages more
3.Culture:
a)Mac Conkey's agar media-Pale colony,incubated at 37^C for overnight.
b)DCA media
4.Serological test:
Confirmatory test done by slide agllutination test with specific antisera.
5.Detection of endotoxin:
Litmus test.
Eita naki CMCr Microbiology departmental head Anwar sir er diagnosis.Oneke mukhostho kore.Shune shune amaro jana hoye gece.
Tarpor amake marar jonno ki shob khay.Shuneci sheguloke naki bole antibiotic.Eder kichhu nam o jante pereci.
Shegulo holo-
1.Ciprofloxacin
2.Ampicillin
3.Cephalosporin
4.Cotrimoxazole.
Ei bishoytake boka manushera nam diyece 'TREATMENT'.
Ha ha ha.Prothomdike khub jhamelay pore gecilam.Ekhon obossho motamuti resistance develope korte pereci.
Ami manusher kachhakachhi thakte pochhondo kori.Oneker sheba (!) korechhi.Hoyto apnaro.Recently ami CMC 49 batch er Jony ebong Kibria ke sheba diyeci.Tara amar shebay nijeder dhonno mone korchhen bole jante perechhi.Tobe onekei achhen amar niyomito shebagrahi.Tader nam prokash kora thik hobe na tai bolci na.Apnara khuje niben.Tobe Muhsin Abdullah namey 1jon mohabir acen.Onek chesta koreo tar kono sheba korte parini bole apnader kachhe khoma prarthona korchhi...
Aj ekhanei biday.Dekha hobe exam er dine.Dhonnobad shobaike.
শুক্রবার, আগস্ট 6, 2010
Amar kichhu 'PROPERTIES'-
1.Gram negative rods
2.Non lactose fermenter
3.We form colorless colonies on Mac Conkey's agar media.
4.Non motile
5.Fimbriae present
6.Aerobes or facultative anaerobes
7.Non spore forming and non capsulated
8.True intestinal.
Ami ja kori takey bola hoy Bacillary dysentry.Eita holo 'frequent painful passage of stools containing blood and mucous.'Vuktovogi matroi er moja ter peyecen.Apni na peye thakle amake janaben.Babostha korbo.
Amar main ostro jake apnara
'VIRULENCE FACTOR' bolen,shegulo holo-
1.Invasiveness
2.Exotoxin-shigella toxin,A & B chain
3.Endotoxin
Amra 4 vai.Apnader vashay 'SPECIES'.Eder namgulo holo-
1.Shigella dysenteriae
2.Shigella flexneri
3.Shigella boydii
4.Shigella sonnei.
Ebar ami apnader bolbo ami kivabe dysentry kori.Apnader vashay
PATHOGENESIS.
Route of entry-Faeco-oral
Infective dose-10-100 organisms to produce disease.
Process-
Terminal ileum>bacteria attach to surface epithelium>enters inside the cells>Spread into adjacent cells>upto lamina propria>replicate and colonize>acute inflammation>micro abscess formation>necrosis of surface epithelium>sloughing out of epithelium>ulcer formation and bleeding from mucosa>endotoxin irritates the bowel causing diarrhoea>organisms remaining localized & usually do not cause bacteremia.
Bachar jonno manushke khete hoy.Oneke acen tara shudhu khaoar jonnoi bachen.Je poriman khan,amaroi voy lage.Abar khushio hoi.Karon etai amar jatayater upojukto poth.Shujog bujhe ami dhuke jai thik peter vetor.Erpor kaj shuru.Oneke bolen 'moddhoprachche juddho shuru hoichhe'.Erpor tibro bege toilet er dike chhute giye comod a missile nikkhep.Ar amar nirapode prosthan.
Majhe majhe bipodeo porte hoy.Amar dhokar khobor peye jan keu keu.Eijonno ja kora hoy takey manushera bole
'DIAGNOSIS'.
Sheta kore evabe-
1.Specimen Collection:-
-Freshly passed stool
-Rectal swab
-Mucous
2.Stool examination:
*Naked eye examination-
Fresh stool
Mucous
Alkaline smell
Pus
*Chemical:
Alkaline in nature
*Microscopic:
Pus cells 90% polymorphs
Epithelial cells more
RBC numerous
Macrophages more
3.Culture:
a)Mac Conkey's agar media-Pale colony,incubated at 37^C for overnight.
b)DCA media
4.Serological test:
Confirmatory test done by slide agllutination test with specific antisera.
5.Detection of endotoxin:
Litmus test.
Eita naki CMCr Microbiology departmental head Anwar sir er diagnosis.Oneke mukhostho kore.Shune shune amaro jana hoye gece.
Tarpor amake marar jonno ki shob khay.Shuneci sheguloke naki bole antibiotic.Eder kichhu nam o jante pereci.
Shegulo holo-
1.Ciprofloxacin
2.Ampicillin
3.Cephalosporin
4.Cotrimoxazole.
Ei bishoytake boka manushera nam diyece 'TREATMENT'.
Ha ha ha.Prothomdike khub jhamelay pore gecilam.Ekhon obossho motamuti resistance develope korte pereci.
Ami manusher kachhakachhi thakte pochhondo kori.Oneker sheba (!) korechhi.Hoyto apnaro.Recently ami CMC 49 batch er Jony ebong Kibria ke sheba diyeci.Tara amar shebay nijeder dhonno mone korchhen bole jante perechhi.Tobe onekei achhen amar niyomito shebagrahi.Tader nam prokash kora thik hobe na tai bolci na.Apnara khuje niben.Tobe Muhsin Abdullah namey 1jon mohabir acen.Onek chesta koreo tar kono sheba korte parini bole apnader kachhe khoma prarthona korchhi...
Aj ekhanei biday.Dekha hobe exam er dine.Dhonnobad shobaike.
শুক্রবার, আগস্ট 6, 2010
কোন মন্তব্য নেই:
একটি মন্তব্য পোস্ট করুন